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Suggested Dosing Chart
The chart presents the dose in both milligrams
and milliliters (mL) of Antizol Solution. Antizol is dosed on a
milligram per kilogram basis. The following chart converts weight
in pounds (lbs) to kilograms (kg).
| Wt.
(lbs) |
Wt.
(kg) |
Loading
Dose (mg)
15mg/kg for 1 dose |
Loading
Dose (mL) |
Initial*
Maintenance Dose (mg)
10mg/kg q12h for 4 doses |
Maintenance
Dose (mL) |
Subsequent
Maintenance Dose (mg)
15mg/kg q12h until EG<20mg/dL |
Maintenance
Dose (mL) |
| 50 |
22.7 |
340 |
0.34 |
230 |
0.23 |
340 |
0.34 |
| 55 |
25.0 |
375 |
0.38 |
250 |
0.25 |
375 |
0.38 |
| 60 |
27.3 |
410 |
0.41 |
270 |
0.27 |
410 |
0.41 |
| 65 |
29.5 |
440 |
0.44 |
300 |
0.30 |
440 |
0.44 |
| 70 |
31.8 |
480 |
0.48 |
320 |
0.32 |
480 |
0.48 |
| 75 |
34.1 |
510 |
0.51 |
340 |
0.34 |
510 |
0.51 |
| 80 |
36.4 |
550 |
0.55 |
360 |
0.36 |
550 |
0.55 |
| 85 |
38.6 |
580 |
0.58 |
390 |
0.39 |
580 |
0.58 |
| 90 |
40.9 |
610 |
0.61 |
410 |
0.41 |
610 |
0.61 |
| 95 |
43.2 |
650 |
0.65 |
430 |
0.43 |
650 |
0.65 |
| 100 |
45.4 |
680 |
0.68 |
450 |
0.45 |
680 |
0.68 |
| 110 |
50.0 |
750 |
0.75 |
500 |
0.50 |
750 |
0.75 |
| 120 |
54.5 |
820 |
0.82 |
550 |
0.55 |
820 |
0.82 |
| 130 |
59.1 |
890 |
0.89 |
590 |
0.59 |
890 |
0.89 |
| 140 |
63.6 |
955 |
0.96 |
640 |
0.64 |
955 |
0.96 |
| 150 |
68.2 |
1025 |
1.03 |
680 |
0.68 |
1025 |
1.03 |
| 160 |
72.2 |
1090 |
1.09 |
730 |
0.73 |
1090 |
1.09 |
| 170 |
77.2 |
1160 |
1.16 |
770 |
0.77 |
1160 |
1.16 |
| 180 |
81.8 |
1230 |
1.23 |
820 |
0.82 |
1230 |
1.23 |
| 190 |
86.4 |
1300 |
1.30 |
860 |
0.86 |
1300 |
1.30 |
| 200 |
90.9 |
1360 |
1.36 |
910 |
0.91 |
1360 |
1.36 |
| 210 |
95.4 |
1430 |
1.43 |
950 |
0.95 |
1430 |
1.43 |
| 220 |
100.0 |
1500 |
1.50 |
1000 |
1.00 |
1500 |
1.50 |
| 230 |
104.5 |
1570 |
1.57 |
1050 |
1.05 |
1570 |
1.57 |
| 240 |
109.1 |
1640 |
1.64 |
1090 |
1.09 |
1640 |
1.64 |
| 250 |
113.6 |
1700 |
1.70 |
1140 |
1.14 |
1700 |
1.70 |
| 260 |
118.2 |
1775 |
1.75 |
1180 |
1.18 |
1775 |
1.75 |
| 270 |
122.7 |
1840 |
1.84 |
1230 |
1.23 |
1840 |
1.84 |
| 280 |
127.2 |
1910 |
1.91 |
1270 |
1.27 |
1910 |
1.91 |
| 290 |
131.8 |
1980 |
1.98 |
1320 |
1.32 |
1980 |
1.98 |
| 300 |
136.4 |
2050 |
2.05 |
1360 |
1.36 |
2050 |
2.05 |
*Antizol induces its own metabolism, so a subsequent
maintenance dose is required after 4 doses (36 hours).
The most frequent adverse reactions to Antizol
are headache (14%), nausea (11%), dizziness, increased drowsiness,
and bad/metallic taste (each 6%). Minor allergic reactions (rash
and eosinophilia) have been reported. Ethylene glycol plasma and
urine levels as well as the presence of urinary oxalate crystals
in ethylene glycol poisoning and methanol plasma levels in methanol
poisoning should be monitored throughout treatment. Dialysis should
be considered in some cases.
For questions of a medical nature, please
call 1-888-867-7426.
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